Clostridium Difficile Colitis ICD-10 Coding Guide

Also known as

  • Clostridioides difficile infection
  • Pseudomembranous colitis
  • C. difficile-associated diarrhea
  • Antibiotic-associated colitis

Abbreviations

  • CDI
  • CDAD
  • C. diff colitis

Clostridium difficile colitis is classified under ICD-10-CM code A04.7, which requires specifying whether the infection is recurrent. Common billable codes include A04.71 (recurrent), A04.72 (not specified as recurrent), and A04.8 (other specified bacterial intestinal infections).

Primary codes

Billable

Billable

Extension

7th character

POA exempt

No

Coding risks

  • Coding based on lab values alone without provider interpretation

Code comparison

Compare key differences between related codes to select the most specific option.

CodeDescriptionScenario
A04.71Enterocolitis due to Clostridium difficile, recurrentC. difficile enterocolitis documented as recurrent after prior treated episode.
A04.72Enterocolitis due to Clostridium difficile, not specified as recurrentC. difficile enterocolitis confirmed, with no documentation of recurrence or prior episode.
A04.8Other specified bacterial intestinal infectionsBacterial intestinal infection identified from a specified organism other than C. difficile or standard categories.

Select the most specific code supported by the encounter documentation. More specific codes improve reimbursement accuracy and reduce audit risk.

Code ranges

Coding risks

Avoid these common coding issues when reporting Clostridium Difficile Colitis.

Impact

Assigning A04.7 without explicit recurrence status may default to A04.72 when A04.71 is supportable.

Mitigation

Consider querying the provider when recurrence status is absent rather than inferring from prior treatment history or repeat testing.

Ancillary and co-coding

Codes commonly reported with the primary diagnosis on the same claim.

Z-code variants

Family history, personal history, or screening encounter codes related to this condition.

Differential codes

Alternative or commonly confused codes to consider when documentation suggests a different condition than the primary diagnosis.

Frequently asked questions

No. The recurrent and not-specified-as-recurrent subcategories are mutually exclusive, so only one A04.7 subcode may be assigned per encounter.

References

Compiled from the following authoritative coding references. Last updated 2026-08-04.

Disclaimer

This page is compiled from authoritative coding references for educational and reference purposes only. It is not medical advice, billing authority, or an official source of ICD-10-CM guidelines. Always verify codes against the current CMS ICD-10-CM Official Guidelines, AHIMA guidance, and your organization’s coding policies. ICD-10-CM is updated annually on October 1.