I21 is a non-billable/non-specific diagnosis code from the 2026 ICD-10-CM used to classify the following condition: Acute myocardial infarction.
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Cardiac infarction
Coronary (artery) embolism
Coronary (artery) occlusion
Coronary (artery) rupture
Coronary (artery) thrombosis
Infarction of heart, myocardium, or ventricle
Myocardial infarction specified as acute or with a stated duration of 4 weeks (28 days) or less from onset
Code, if applicable, to identify:
Exposure to environmental tobacco smoke (Z77.22)
History of tobacco dependence (Z87.891)
Occupational exposure to environmental tobacco smoke (Z57.31)
Status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
Tobacco dependence (F17.-)
Tobacco use (Z72.0)
ST elevation (STEMI) myocardial infarction of anterior wall
ST elevation (STEMI) myocardial infarction of inferior wall
ST elevation (STEMI) myocardial infarction of other sites
ST elevation (STEMI) myocardial infarction of unspecified site
Non-ST elevation (NSTEMI) myocardial infarction
Acute myocardial infarction, unspecified
Other type of myocardial infarction
Myocardial infarction with coronary microvascular dysfunction
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