R78 is a non-billable/non-specific diagnosis code from the 2025 ICD-10-CM used to classify the following condition: Findings of drugs and other substances, not normally found in blood.
Use additional code
- Code to identify the any retained foreign body, if applicable (Z18.-) 
Type 2 excludes
- Mental or behavioral disorders due to psychoactive substance use (F10-F19) 
Codes
- R78.0- Finding of alcohol in blood 
- R78.1- Finding of opiate drug in blood 
- R78.2- Finding of cocaine in blood 
- R78.3- Finding of hallucinogen in blood 
- R78.4- Finding of other drugs of addictive potential in blood 
- R78.5- Finding of other psychotropic drug in blood 
- R78.6- Finding of steroid agent in blood 
- R78.7- Finding of abnormal level of heavy metals in blood 
- R78.8- Finding of other specified substances, not normally found in blood 
- R78.9- Finding of unspecified substance, not normally found in blood 
Versions
- 2025- No changes 
- 2024- Code changed - Type 1 excludes- mental or behavioral disorders due to psychoactive substance use (F10-F19)
 
 
- Type 2 excludes- mental or behavioral disorders due to psychoactive substance use (F10-F19)
 
 
 
- 2023- No changes 
- 2022- No changes 
- 2021- No changes 
- 2020- No changes 
- 2019- No changes 
- 2018- No changes 
- 2017- No changes 
- 2016- New code