Metabolic Encephalopathy ICD-10 Coding Guide

Also known as

  • Toxic-metabolic encephalopathy
  • Metabolic brain dysfunction

Abbreviations

  • TME

The ICD-10-CM code for metabolic encephalopathy is G93.41 (Metabolic encephalopathy), a billable code reported when brain dysfunction results from an underlying metabolic disturbance rather than a structural or primary neurological cause.

Primary codes

Billable

Billable

Extension

7th character

POA exempt

No

Inclusion terms

  • Septic encephalopathy

Coding risks

  • Missing a required companion or status code

Code comparison

Compare key differences between related codes to select the most specific option.

CodeDescriptionScenario
G93.41Metabolic encephalopathyEncephalopathy attributed to a documented metabolic cause such as hepatic, uremic, or electrolyte disturbance.
G93.40Encephalopathy, unspecifiedEncephalopathy documented without a specified type, cause, or metabolic etiology in the chart.
G93.49Other encephalopathyEncephalopathy with a specified cause documented that is not metabolic, anoxic, toxic, or another dedicated subtype.

Select the most specific code supported by the encounter documentation. More specific codes improve reimbursement accuracy and reduce audit risk.

Code ranges

Coding risks

Avoid these common coding issues when reporting Metabolic Encephalopathy.

Impact

Assigning G93.41 without explicit metabolic cause may miscode as toxic encephalopathy (G92) or unspecified (G93.40).

Mitigation

Consider querying the provider when etiology is absent rather than inferring from lab abnormalities or medication lists.

Ancillary and co-coding

Codes commonly reported with the primary diagnosis on the same claim.

Differential codes

Alternative or commonly confused codes to consider when documentation suggests a different condition than the primary diagnosis.

Frequently asked questions

Use G93.40 only when the provider documents encephalopathy without specifying a cause. If metabolic etiology is documented, assign G93.41 instead.

References

Compiled from the following authoritative coding references. Last updated 2026-08-04.

Disclaimer

This page is compiled from authoritative coding references for educational and reference purposes only. It is not medical advice, billing authority, or an official source of ICD-10-CM guidelines. Always verify codes against the current CMS ICD-10-CM Official Guidelines, AHIMA guidance, and your organization’s coding policies. ICD-10-CM is updated annually on October 1.