The ICD-10-CM code for thrombocytopenia is D69.6 (Thrombocytopenia, unspecified), a billable code reported when a low platelet count is documented without specification of the underlying cause or type.
Primary codes
Billable
Billable
Extension
—
7th character
—
POA exempt
No
Coding risks
- Assigning when documentation supports a more specific code
Hierarchy
Code comparison
Compare key differences between related codes to select the most specific option.
| Code | Description | Scenario |
|---|---|---|
| D69.6 | Thrombocytopenia, unspecified | Thrombocytopenia documented without specified cause, mechanism, or immune, hereditary, or secondary etiology. |
| D69.3 | Immune thrombocytopenic purpura | ITP confirmed as autoimmune platelet destruction, no secondary cause or congenital origin identified. |
| D69.59 | Other secondary thrombocytopenia | Thrombocytopenia attributed to an identified external cause such as drugs, infection, or transfusion. |
| D69.49 | Other primary thrombocytopenia | Primary thrombocytopenia documented, not immune-mediated and not congenital or hereditary in origin. |
| D69.42 | Congenital and hereditary thrombocytopenia purpura | Thrombocytopenia present from birth or inherited, such as Wiskott-Aldrich or other congenital syndromes. |
Select the most specific code supported by the encounter documentation. More specific codes improve reimbursement accuracy and reduce audit risk.
Code ranges
Purpura and other hemorrhagic conditions
Category D69 covers purpura, qualitative platelet defects, and thrombocytopenia from various acquired or congenital causes.
Coagulation defects, purpura and other hemorrhagic conditions
This sub-chapter groups disorders of hemostasis including coagulation factor deficiencies, DIC, purpura, and platelet disorders.
Other disorders of blood and blood-forming organs
Covers neutropenia, agranulocytosis, functional disorders of polymorphonuclear neutrophils, and other conditions of blood-forming organs.
Other perinatal hematological disorders
Perinatal-onset hematological conditions in newborns including transient neonatal thrombocytopenia and other blood disorders originating in the perinatal period.
Diseases of the blood in pregnancy, childbirth and the puerperium
Obstetric codes for maternal blood and blood-forming organ diseases complicating pregnancy, delivery, or the postpartum period.
Coding risks
Avoid these common coding issues when reporting Thrombocytopenia.
Impact
Assigning D69.6 without documented etiology may miscode as immune (D69.3) or drug-induced (D69.59) thrombocytopenia.
Mitigation
Consider querying the provider when etiology is absent rather than inferring from concurrent medications or comorbidities.
Related codes
Ancillary and co-coding
Codes commonly reported with the primary diagnosis on the same claim.
Z-code variants
Family history, personal history, or screening encounter codes related to this condition.
In pregnancy
Pregnancy-specific O-code adaptations used in place of the primary when the condition occurs during or complicates pregnancy.
Differential codes
Alternative or commonly confused codes to consider when documentation suggests a different condition than the primary diagnosis.
Frequently asked questions
Use D69.6 only when the chart documents thrombocytopenia without a specified cause. Immune, congenital, or secondary etiologies require more specific codes.
References
Compiled from the following authoritative coding references. Last updated 2026-08-04.