D89.4 is a non-billable/non-specific diagnosis code from the 2025 ICD-10-CM used to classify the following condition: Mast cell activation syndrome and related disorders.
Type 1 excludes
Aggressive systemic mastocytosis (C96.21)
Congenital cutaneous mastocytosis (Q82.2)
(non-congenital) cutaneous mastocytosis (D47.01)
(indolent) systemic mastocytosis (D47.02)
Malignant mast cell neoplasm (C96.2-)
Malignant mastocytoma (C96.29)
Mast cell leukemia (C94.3-)
Mast cell sarcoma (C96.22)
Mastocytoma NOS (D47.09)
Other mast cell neoplasms of uncertain behavior (D47.09)
Systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.02)
Codes
Versions
2025
No changes
2024
No changes
2023
No changes
2022
No changes
2021
No changes
2020
No changes
2019
No changes
2018
Code changed
Type 1 excludes
aggressive systemic mastocytosis (C96.2)cutaneous mastocytosis (Q82.2)indolent systemic mastocytosis (D47.0)malignant mastocytoma (C96.2)mast cell leukemia (C94.3-)mastocytoma (D47.0)systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.0)
- aggressive systemic mastocytosis (C96.21)
- congenital cutaneous mastocytosis (Q82.2)
- (non-congenital) cutaneous mastocytosis (D47.01)
- (indolent) systemic mastocytosis (D47.02)
- malignant mast cell neoplasm (C96.2-)
- malignant mastocytoma (C96.29)
- mast cell leukemia (C94.3-)
- mast cell sarcoma (C96.22)
- mastocytoma NOS (D47.09)
- other mast cell neoplasms of uncertain behavior (D47.09)
- systemic mastocytosis associated with a clonal hematologic non-mast cell lineage disease (SM-AHNMD) (D47.02)
2017
New code