2025
ICD-10-CM
Diagnosis
Code

D89.83 Cytokine release syndrome

  • Non-billable
  • 2021–2025

D89.83 is a non-billable/non-specific diagnosis code from the 2025 ICD-10-CM used to classify the following condition: Cytokine release syndrome.

Code first

  • Underlying cause, such as:

    • Complications following infusion, transfusion and therapeutic injection (T80.89-)

    • Complications of transplanted organs and tissue (T86.-)

Use additional code

  • Code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

Codes

Versions

  1. 2025

    Code changed

    • Use additional code

        • code to identify associated manifestations
        • code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

  2. 2024

    No changes

  3. 2023

    No changes

  4. 2022

    No changes

  5. 2021

    New code