2026
ICD-10-CM
Diagnosis
Code

Z17.421 Hormone receptor negative with human epidermal growth factor receptor 2 negative status

  • Billable
  • POA Exempt
  • 2025–2026

Z17.421 is a billable/specific and POA-exempt diagnosis code from the 2026 ICD-10-CM used to classify the following condition: Hormone receptor negative with human epidermal growth factor receptor 2 negative status.

Inclusion term

  • HR- with HER2-

  • TNBC

  • Triple negative breast cancer

Versions

  1. 2026

    No changes

  2. 2025

    New code