2025
ICD-10-CM
Diagnosis
Code

Z79.81 Long term (current) use of agents affecting estrogen receptors and estrogen levels

Non-billable
2016–2025

Z79.81 is a non-billable/non-specific diagnosis code from the 2025 ICD-10-CM used to classify the following condition: Long term (current) use of agents affecting estrogen receptors and estrogen levels.

Code first

If applicable:

Malignant neoplasm of breast (C50.-)
Malignant neoplasm of prostate (C61)

Use additional code

Code, if applicable, to identify:

Estrogen receptor positive status (Z17.0)
Family history of breast cancer (Z80.3)
Genetic susceptibility to malignant neoplasm (cancer) (Z15.0-)
Personal history of breast cancer (Z85.3)
Personal history of prostate cancer (Z85.46)
Postmenopausal status (Z78.0)

Type 1 excludes

Hormone replacement therapy (Z79.890)

Codes

Versions

2025
No changes
2024
No changes
2023
No changes
2022
No changes
2021
No changes
2020
No changes
2019
No changes
2018
Code changed
- Type 1 excludes
  ~~hormone replacement therapy (postmenopausal) (Z79.890)~~
  hormone replacement therapy (Z79.890)
2017
No changes
2016
New code