C21 is a non-billable/non-specific diagnosis code from the 2026 ICD-10-CM used to classify the following condition: Malignant neoplasm of anus and anal canal.
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Malignant carcinoid tumors of the colon (C7A.02-)
Malignant melanoma of anal margin (C43.51)
Malignant melanoma of anal skin (C43.51)
Malignant melanoma of perianal skin (C43.51)
Other and unspecified malignant neoplasm of anal margin (C44.500, C44.510, C44.520, C44.590)
Other and unspecified malignant neoplasm of anal skin (C44.500, C44.510, C44.520, C44.590)
Other and unspecified malignant neoplasm of perianal skin (C44.500, C44.510, C44.520, C44.590)
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