2025
ICD-10-CM
Diagnosis
Code

C49 Malignant neoplasm of other connective and soft tissue

  • Non-billable
  • 2016–2025

C49 is a non-billable/non-specific diagnosis code from the 2025 ICD-10-CM used to classify the following condition: Malignant neoplasm of other connective and soft tissue.

Includes

  • Malignant neoplasm of blood vessel

  • Malignant neoplasm of bursa

  • Malignant neoplasm of cartilage

  • Malignant neoplasm of fascia

  • Malignant neoplasm of fat

  • Malignant neoplasm of ligament, except uterine

  • Malignant neoplasm of lymphatic vessel

  • Malignant neoplasm of muscle

  • Malignant neoplasm of synovia

  • Malignant neoplasm of tendon (sheath)

Type 1 excludes

  • Malignant neoplasm of cartilage (of):

    • Articular (C40-C41)

    • Larynx (C32.3)

    • Nose (C30.0)

    • Malignant neoplasm of connective tissue of breast (C50.-)

Type 2 excludes

  • Kaposi's sarcoma of soft tissue (C46.1)

  • Malignant neoplasm of heart (C38.0)

  • Malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)

  • Malignant neoplasm of peritoneum (C48.2)

  • Malignant neoplasm of retroperitoneum (C48.0)

  • Malignant neoplasm of uterine ligament (C57.3)

  • Mesothelioma (C45.-)

Codes

Versions

  1. 2025

    No changes

  2. 2024

    No changes

  3. 2023

    No changes

  4. 2022

    No changes

  5. 2021

    No changes

  6. 2020

    No changes

  7. 2019

    No changes

  8. 2018

    No changes

  9. 2017

    No changes

  10. 2016

    New code